Zoloft Vs Lexapro

Difference Between zoloft and lexapro

With regards to antidepressants, patients regularly give various medications before settling on a shot one that works best for them. Lexapro (Escitalopram) and Zoloft (Sertraline) are both remedy SSRI antidepressants recommended to treat gloom and nervousness. 

Generic version of Lexapro is Escitalopram. Generic version of Zoloft is Sertraline. They work by reestablishing the parity of synapses like serotonin. The thing that matters is that Zoloft can treat a few extra manifestations. However, Lexapro has a quicker delivery time. Lexapro (Escitalopram) and Zoloft (Sertraline) likewise have distinctive reactions.

Comparison based on the utilization of Lexapro and Zoloft

Lexapro (Escitalopram), a Selective Serotonin Reuptake Inhibitor (SSRI), works by reestablishing the parity of synapses like serotonin. Specialists recommend Lexapro to treat despondency and nervousness. Lexapro must be recommended and is taken orally once every day, for the most part simultaneously of the day.


Zoloft (Sertraline) is additionally an SSRI that works by reestablishing the parity of synapses (serotonin). Specialists recommend Zoloft to treat misery, over the top urgent issue, alarm assaults, post-horrible pressure issue, social uneasiness issue and premenstrual dysphoric issue.


Zoloft is additionally prescribed and is taken once every day after weakening, as a rule simultaneously of the day.

Lexapro (escitalopram) is useful for treating misery and tension. It is less inclined to cause symptoms than and has fewer medication associations. Be that as it may, it probably won’t be a decent decision in the event that you have liver or heart issues.

Zoloft (sertraline) is useful for treating melancholy and tension. However, it can connect with numerous medications.

Comparison based on the reaction of Lexapro and Zoloft

The utilization of Lexapro (Escitalopram) just as Zoloft (sertraline) can prompt a few symptoms. Individuals utilizing Lexapro may encounter tipsiness, sleepiness stoppage, dry mouth, expanded perspiring, a sleeping disorder, sickness or sluggishness.


Pregnant ladies may take Lexapro, yet there is a danger of birth deserts. A portion of the more extreme reactions may incorporate disarray, trouble concentrating, rapture, self-destructive musings, low sex drive and diminished sexual capacity.


Some reactions are uncommon, yet at the same time likely – these incorporate forceful conduct, hypertension, coronary episode, blood clusters, quick heartbeat, slow heartbeat, drain, kidney disappointment and seizures.


Zoloft patience may encounter dizziness, sluggishness, the runs, dry mouth, expanded perspiring, sleep deprivation, loss of hunger, queasiness or an annoyed stomach. As with Lexapro, pregnant ladies may utilize the medication. However, there is a danger of birth abandonment. Regular extreme reactions incorporate self-destructive musings, low sex drive and diminished sexual capacity.


Uncommon reactions incorporate a fast ventricular heartbeat, a moderate heartbeat, discharge, liver disappointment, intense kidney illness and happiness.

Comparison based on the withdrawal symptoms of Lexapro and Zoloft

Specialists suggest patients stop utilizing Lexapro or Zoloft just under clinical watch. Patients stopping either medication may encounter withdrawal manifestations.

The withdrawal manifestations from Lexapro incorporate disarray, cerebral pain, a sleeping disorder, apprehension, deadness and shivering. Stopping the utilization of Zoloft may prompt cerebral pains, state of mind swings, rest changes, sleepiness or a concise sensation, for example, an electric stun.

Comparison based on the warnings of Lexapro and Zoloft

Before taking either Lexapro or Zoloft, patients need to uncover their whole clinical history to their primary care physician. Drinking liquor isn’t suggested with the utilization of either tranquilizer. Driving or working hardware ought to likewise be evaded while utilizing Lexapro or Zoloft.

 Any mental issues, self-destruction endeavors, draining issues, liver malady, seizures, kidney illness, stomach dying, drying out and low sodium in the blood ought to be referenced before choosing to utilize Lexapro.

Zoloft may not function admirably if patients have had draining issues, liver infection, seizure issues and thyroid malady. Medication Interactions

Patients should know about medication associations with both Lexapro and Zoloft. Neither one of them works well along with MAO inhibitors, for example, isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, selegiline or tranylcypromine. The outcomes can be deadly.

 Both Lexapro and Zoloft increment the danger of draining while collaborating with the accompanying medications: Pimozide, antiplatelet drugs, NSAIDs, blood thinners and anti-inflammatory medications. An expansion of sluggishness happens when either Lexapro or Zoloft connects with antihistamines, rest or nervousness drugs, muscle relaxants or opiate torment relievers.

Explicit medication communications can prompt serotonin condition. Those medications incorporate dextromethorphan, lithium, Individuals experiencing serotonin disorder experience a few impacts. Their psychological status can change with the goal that they experience unsettling, incoherence or fantasies.

They may even go into a state of unconsciousness. Unsteadiness, flushing, hyperthermia and tachycardia are indications of autonomic shakiness. Neuromuscular impacts incorporate incoordination, inflexibility and quakes.

Individuals with serotonin disorder can experience the ill effects of gastrointestinal issues, for example, loose bowels, sickness or retching. They might be inclined to seizures.

Serotonin disorder is a reaction of blending either Lexapro or Zoloft with explicit prescriptions.

Comparison based on the Capacity and Shelf Life of Lexapro and Zoloft

Lexapro is the more current of the two medications, accepting FDA endorsement in 2002. Zoloft got FDA endorsement in 1991. Both ought to be put away at room temperature with no light or dampness. Kept that way, Lexapro has a time span of usability of three years and Zoloft five years. Neither one of the medications ought to be flushed or washed down the channel.

Both Lexapro and Zoloft have a place with the class of prescriptions called specific serotonin reuptake inhibitors (SSRIs) and are both FDA endorsed to treat nervousness and gloom. Both are accessible in tablet and fluid structures. The fundamental contrasts among Lexapro and Zoloft are:

  • Lexapro is a marked form of escitalopram and Zoloft is a marked variant of sertraline
  • Zoloft is likewise FDA endorsed to treat OCD (over the top enthusiastic issue), alarm issue, PTSD (post-horrendous pressure issue), social fear, and premenstrual dysphoric issue (PDD)
  • There are a few contrasts in their symptoms with Lexapro being bound to mess rest up and taste aggravations, and Zoloft is bound to cause a skin rash or loose bowels.
  • There is some proof that Lexapro might be more powerful than different SSRIs, including Zoloft, in the treatment of wretchedness.

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